Mechanism, half-life, literature. No dosing on the public side. Not medical advice.
Fourteen compounds, their mechanisms, half-lives, and where the literature lives. The reference sheet I wished existed when I started buying peptides. Built for operators who want to know what each molecule actually does before they read anyone's stack post.
Download free →Harvard Science Review said 39% of weight lost on semaglutide is lean mass. The methodology has been pushed back on for years, and a January 2026 longitudinal study now reads it differently. The synthesis you have not seen — plus the five peptides operators stack with their GLP-1.
Download free →Topical vs. systemic, and the regulatory split. GHK-Cu, PT-141, Epitalon, Thymosin Beta-4, copper-peptide hair serums, Melanotan II (with the cardiovascular caveat flagged), Cerebrolysin. Seven compounds, evidence tier per row, no marketing.
Download free →BPC-157, TB-500, GHK-Cu, PDA, Larazotide. The recovery lane, walked through with the same tier framework as the rest of The Brief. Sikiric corpus framed as preclinical. Fragment-vs-parent peptide distinction surfaced. What we don't know yet, openly.
Download free →After you download, you also subscribe to the Sunday briefing — five to seven minutes, every Sunday at 9am ET. Mechanism, half-life, literature, regulatory beat, vendor field reports. Unsubscribe in one click whenever the signal stops being worth the inbox.